Methionine sulfoximine reduces cortical infarct size in rats after middle cerebral artery occlusion.
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Methionine sulfoximine reduces cortical infarct size in rats after middle cerebral artery occlusion.
The methionine analogue methionine sulfoximine was administered to 10 rats 24 hours before occlusion of the proximal left middle cerebral artery. Three days later the rats were decapitated and the brain infarct volumes were compared with those in 10 control rats that received saline before middle cerebral artery occlusion. The mean volume of the infarct in the cerebral cortex was reduced by 33%...
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ژورنال
عنوان ژورنال: Stroke
سال: 1990
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.21.2.322